Ebook Crystals, X-rays and Proteins: Comprehensive Protein CrystallographyBy Dennis Sherwood, Jon Cooper

Ebook Crystals, X-rays and Proteins: Comprehensive Protein CrystallographyBy Dennis Sherwood, Jon Cooper

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Crystals, X-rays and Proteins: Comprehensive Protein CrystallographyBy Dennis Sherwood, Jon Cooper

Ebook Crystals, X-rays and Proteins: Comprehensive Protein CrystallographyBy Dennis Sherwood, Jon Cooper

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A complete account of the theory of the diffraction of X-rays by crystals, with particular reference to the processes of determining the structures of protein molecules. This book is aimed primarily at structural biologists and biochemists but will also be valuable to those entering the field with a background in physical sciences or chemistry. It may be used at any post-school level, and develops from first principles all relevant mathematics, diffraction and wave theory, assuming no mathematical knowledge beyond integral calculus.

The book covers a host of important topics in the area, including:
- The practical aspects of sample preparation and X-ray data collection, using both laboratory and synchrotron sources
- Data analysis at both theoretical and practical levels
- The important role played by the Patterson function in structure analysis, by both molecular replacement and experimental phasing approaches
- Methods for improving the resulting electron density map
- The theoretical basis of methods used in refinement of protein crystal structures
- In-depth explanation of the crucial task of defining the binding sites of ligands and drug molecules
- The complementary roles of other diffraction methods: these reveal further detail of great functional importance in a crystal structure.

• Sales Rank: #1609651 in Books
• Published on: 2015-05-24
• Released on: 2015-05-24
• Original language: English
• Number of items: 1
• Dimensions: 6.70" h x 1.20" w x 9.70" l, 2.76 pounds
• Binding: Paperback
• 640 pages

Review
"The first two-thirds of this book was like a thriller to me. Even though I knew the answer, I wanted to see how the author would address the next topic and I could not put it down." --Joseph D. Ferrara, Ph.D, Crystallography Times

"This is one of the best crystallography books ever written, and it is with pleasure that I wholeheartedly recommend it." --Nicholas M. Glykos, Democritus University of Thrace, Greece 24/10/2012

"The authors have nicely brought the bibliography up to date and mention recent method developments, giving a good first grasp of what is involved in solving a structure. The text also makes good use of accompanying, illustrative figures, which is most essential when developing the complex concepts of diffraction, Fourier transformation and convolution." --E. von Castelmur and A. Perrakis, Crystallography Reviews June 2011

"In my opinion, this book would be the perfect textbook for a theoretical course on macromolecular crystallography" --Manfred S. Weiss, Acta Crystallographica Section D Jan 2012

"A welcome addition to any structural biology laboratory, [and] an invaluable reference, answering questions in an accurate and transparent manner" --Karen McLuskey, Chemistry World March 2011

About the Author

Dennis Sherwood, Managing Director, The Silver Bullet Machine Manufacturing Company,Jon Cooper, Professor of Structural Biology, Division of Medicine, University College London

Dennis Sherwood read Natural Sciences as a scholar at Clare College, Cambridge, and subsequently won a Mellon Fellowship to the Department of Molecular Biophysics and Biochemistry at Yale University (MPhil), and a Calbiochem Scholarship to the University of California at San Diego (PhD). After a brief period as an ICI Post-doctoral Fellow at the University of Sussex, Dennis changed career, and joined Deloitte Haskins & Sells as a trainee consultant, and where, for 12 years, he was a consulting partner. Dennis was subsequently an Executive Director with Goldman Sachs, a partner in Bossard Consultants, and Managing Director in the UK of SRI Consulting. Dennis now runs his own business, The Silver Bullet Machine Manufacturing Company Limited , which specialises in organizational creativity and innovation. Dennis participates in a number of academic programmes at institutions such as London Business School, the London School of Economics, the University of St Gallen, and London South Bank University.

Jon Cooper is a Professor of Structural Biology at UCL Department of Medicine who specialises in expression and X-ray structure analysis of proteins. Previously he was based in the School of Biological Sciences at the University of Southampton where he taught biochemistry and structural biology on undergraduate programmes and at the post-graduate level. He has been working in the protein crystallography field since the mid-1980s when he started a PhD at Birkbeck College London where he later became a post-doctoral fellow and subsequently a lecturer. He is a member of Biological Structures Group of the British Crystallographic Association (BCA) and has been a tutor at the BCA Protein Crystallography Summer School.

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Crystals, X-rays and Proteins: Comprehensive Protein CrystallographyBy Dennis Sherwood, Jon Cooper PDF

Crystals, X-rays and Proteins: Comprehensive Protein CrystallographyBy Dennis Sherwood, Jon Cooper PDF

Crystals, X-rays and Proteins: Comprehensive Protein CrystallographyBy Dennis Sherwood, Jon Cooper PDF

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Free Download Trump University Asset Protection 101By J. J. Childers

Free Download Trump University Asset Protection 101By J. J. Childers

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Trump University Asset Protection 101By J. J. Childers

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A tax-smart guide to keeping more of the wealth you build Three obstacles to wealth-lawsuits, income taxes, and estate taxes-can and will destroy the financial achievements of those who fail to properly safeguard their assets. In this book, attorney and tax strategist J.J. Childers lays out a plan for combating these forces so that anyone willing to learn and apply the secrets of the wealthy can do so in a smart, simple, and effective way. J.J. Childers (Little Rock, AR) is a licensed attorney specializing in wealth structures that reduce taxes and shield assets. He speaks on these topics to thousands of individuals, investors, and small business owners each year. His unique ability to explain complicated strategies in simple terms has made him one of the nation's most sought-after speakers and practitioners on asset-protecting legal structures.

• Amazon Sales Rank: #615330 in Books
• Published on: 2007-10-19
• Original language: English
• Number of items: 1
• Dimensions: 9.30" h x 1.12" w x 6.30" l, 1.05 pounds
• Binding: Hardcover
• 288 pages

From the Inside Flap

There are three things that will destroy your hard-earned wealth faster than anything else: income taxes, lawsuits, and estate taxes. The wealthy know this and use the kind of strategies found in this book to protect their fortunes. Unfortunately, most people focus on playing "offense" with their money, and forget all about protecting it by playing financial defense—until they get blindsided. Trump University Asset Protection 101 gives you the power to protect and grow your wealth at the same time, no matter how much or how little you have in the bank.

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• Massive tax deductions the rich use every day

• How owning your own business can save you a fortune

• Protecting yourself against lawsuits

• Using business entities and tax structures to keep assets out of the reach of others

• Why you must have an estate plan, no matter how young you are

Building wealth is useless if you can't protect it from the government and other people who want to take it away from you. Trump University Asset Protection 101 gives you all the tools you need to avoid the three big obstacles to wealth creation and protection—lawsuits, income taxes, and estate taxes. You don't have to be Donald Trump to use these strategies, but you do have to be just as smart about protecting your hard-earned wealth.

From the Back Cover

Trump University Asset Protection 101

Trump University books are practical, straightforward primers on the basics of doing business the Trump way—successfully. Each book is written by leading experts in the field and includes contributions from Mr. Trump himself. Perfect for anyone who wants to get ahead in business without the MBA, these streetwise books provide real-world business advice based on the one thing readers can't get in any business school—experience.

In Trump University Asset Protection 101, you'll learn how to:

• Utilize the most powerful money-saving tax deductions

• Use your small business as a big tax shelter

• Use exemptions to help guard your assets

• Give your assets a makeover with a Multiple Entity Structuring Strategy

• Protect assets through gifting and philanthropy

• Maximize tax benefits from your retirement money

• Combine multiple strategies for a smart, long-term asset protection plan

About the Author

J.J. Childers is an attorney specializing in wealth structures that reduce taxes and shield assets. He speaks on these topics to thousands of individuals, investors, and small business owners each year. His unique ability to explain complicated wealth-protection strategies in simple terms has made him one of the nation's most sought-after experts on asset-protecting legal structures.

Trump University Asset Protection 101By J. J. Childers PDF
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Ebook Free Humans Need Not Apply: A Guide to Wealth and Work in the Age of Artificial Intelligence

Ebook Free Humans Need Not Apply: A Guide to Wealth and Work in the Age of Artificial Intelligence

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Humans Need Not Apply: A Guide to Wealth and Work in the Age of Artificial Intelligence

Ebook Free Humans Need Not Apply: A Guide to Wealth and Work in the Age of Artificial Intelligence

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Audible Audiobook

Listening Length: 5 hours and 58 minutes

Program Type: Audiobook

Version: Unabridged

Publisher: Tantor Audio

Audible.com Release Date: March 15, 2016

Whispersync for Voice: Ready

Language: English, English

ASIN: B01CONM4RM

Amazon Best Sellers Rank:

For me, I found this book to be one of the most thought provoking books that I have ever read. Mr, Kaplan has placed much thought and most of all research in the field of Al. Basically, he has calculated data and information to explain how this will grow in the future.Each chapter I found meaningful. My favorite chapters were:. Chapter 4 ... The Gods Are Angry. This chapter spoke volumes to me personally because I like to go on the internet and do searches in search engines. Really, until I read this book, I did not give this much thought at all. After I read this chapter, I was shocked to discover the part about synthetic intellects. In fact, this particular chapter, I read twice!. Chapter 8 Take This Job And Automate It - This is a very thought provoking chapter. Mr Kaplan gives excellent examples of how the internet and more are affecting jobs. He gave a great example of attornies...in thus day of going onto the internet and one obtaining a legal form and using it is very true!I also like the fact that the author placed an index in this book. After I read the book, I wanted to go back and look up several subjects.Humans Need Not Apply (hardback version) sample was provided. I agreed to give an unbiased review. In my opinion, I really am happy that I read this book as it is really food for thought. This is a very impressive book and I highly recommend this book.

Jerry Kaplan does for the future what Jared Diamond did for the past: He pulls together our human (or humanoid) fate in sparkling,often hilarious, prose. Kaplan begins by offering the non scientific reader (me) a clear overview of the AI advances that are poised to make human workers obsolete--offering eye popping examples explaining how the pace of technology is destined to overwhelm the human landscape of life and work. He then charts the changes that span FAR more than driverless cars. Mechanical robots (or what Kaplan calls "forged intelligences") will be more adept (and. of course, far more cost effective) than humans at performing every routine job from collecting our garbage to stocking our grocery shelves (and make those physical stores quaint relics of the past). "Synthetic intelligences" (machines that think and analyze information) will outwit humans at making complex diagnoses or writing legal briefs--automating out many of the hapless law school or medical students spending decades accumulating those mountainous student debts .So far readers may be saying " I know all that stuff". Actually, you don't. The real gem of this book is that Kaplan CALCULATES how many people enter the workforce with those mountains of debt and compares their expected salaries. He analyzes the current employment situation for new law school grads and other "knowledge workers". He offers a wealth of data documenting how many jobs are going to be lost... beginning with that prime exemplar (AKA job wrecker), Amazon. I always wanted to know how Amazon evolved, the truth about this behemoth's business model, and how many jobs Amazon has automated out... In this book you will actually get these statistics and much more, as well as learning exactly why those standard government "job growth projection" stats are apt to be totally wrong.In other words, as you read in these other reviews , this book is all about income inequalities and what we can do to in Kaplan's words to slow the transition to making "America the Land of the Pharaohs" ( You ain't seen nothing yet). In fact the chapter--of this title- describing the lifestyles of Kaplan and his much richer colleagues versus one of his hardworking employees is the best in- the- flesh description of income inequalities I've read. Kaplan has the huge advantage of personally knowing these billionaire Silicon Valley movers and shakers--in addition to having a birds eye seat on how these technologies evolved. But, most important, he has a gift for bringing it all home through creative analogies and zinger-like sentences that had me rolling on the floor. So if you like Jared Diamond, or even if you don't know who he is, you will LOVE this landmark book.P.S. I've omitted the fact that Kaplan also suggests answers.. that is, he devises highly innovative policy suggestions to make playing field less steep that come closer to attacking the roots of the problem and go well beyond the current mantras such as increasing access to college or raising the minimum wage......

A sizeable of very good books on the impact of technology on jobs have come out within the past 4 or so years written by a number of individual eminently qualified individuals. Such books have included Tyler Cowen’s “Average is Over”, Eric Brynjolfoson and Andrew McAfee’s “The Second Machine Age: Work, Progress, and Prosperity in a Time of Brilliant Technologies”, Jaron Lanier’s “Who Owns the Future?” and Martin Ford’s “Rise of the Robots: Technology and the Threat of a Jobless Future”. These authors represent a wide variety of fields, from academic economists (Cowen and Brynjolfson), software programmers and engineers (McAfee and Lanier) and financiers involved in angel funding of high tech firms (Ford has a graduate degree in engineering and an MBA and is involved in finding and funding high tech companies with new and innovative technologies). Unfortunately, none of these individuals, simultaneously, have a technical degree, experience “creating” in the high-tech field and an academic background. Dr Kaplan, the author of “Humans Need Not Apply”, however does have such a background and this reviewer thought that, for that reason, he may be able to shed a different perspective on the topic or new insights from a different set of angles.Reading the introduction, this reviewer was happy to see that this is the type of book the author himself wrote with the purpose of fulfilling. On p. 16 of the introduction (hardcopy edition), Dr Kaplan writes: “ My goal in this book is to equip you with the intellectual tools, ethical foundation, and psychological framework required to successfully navigate these challenges [challenges of seeing how technology will impact employment]…Of course many talented and thoughtful writers have already rung the alarm about the risks of recent technological advances…My goal here is to add a different voice to the growing chorus of concern, mine from the perspective of the technology entrepreneur.”Dr Kaplan then goes about putting forth the argument, very persuasively, that technological advances on many fronts will lead to massive unemployment. For example, self-driving automobiles and trucks will put millions of vehicle drivers out of work and DIDO technology (distributed input, distributed output) will put the installers of internet cables out of work. He believes that this automation will lead to very widespread unemployment and will threaten the livelihoods of the overwhelming majority of the workforce. The proverbial 99% to be more exact. This is the same conclusion reached by every one of the other authors mentioned above.The only disappointing fact in this book is that the discussion of the relevant technologies is not very in-depth. For a much more in-depth analysis this reviewer highly recommends the other books cited above, in particular Ford’s “The Rise of the Robots” instead. Then again Ford’s book, as most of the other books mentions above, are about double the length of Kaplan’s. Ford’s book for example, is about 370 pages in length (full size text pages) while Kaplan’s is less than half that (about 210 small pages).Dr Kaplan then goes about spelling out a possible “solution” to this problem. This is two pronged. One involves granting workers a kind of mortgage grant in terms of education spending that will enable them to re-tool. This is analogous to Milton Friedman’s idea of the govt providing people with educations and, simultaneously, making the payback terms a function of their future income streams. However there are 2 problems here. The first is that technology does not advance so quickly that that workers cannot gain skills quicker than they are rendered obsolete by technology. Secondly, that there are actually positions to train for. Hence this solution is very problematic.The second half of the prong involves granting workers a capital ownership interest in the companies producing the automation. This will provide those workers with dividend incomes that will enable them to survive in a world with massive unemployment. Plus it will not deter their incentives to work (the dividend payments would not be very high) and the incentives for technological progress would not be negated.This sounds nice but does have a number of problems associated with it, unfortunately none of which the author examines. One is that the owners of these companies would have to agree with having their ownership in their own companies seriously diluted. A second problem would be that doing this may so inflate capital ownership that the returns of capital would be significantly curtailed, thus making it difficult for this strategy to provide the unemployed (the overwhelming majority of society) with a sufficient income to to survive on.Thus Dr. Kaplan’s solution seems very weak. Then again so do those of many of the other authors mentioned above to the problem of massive unemployment. For example, Brynjolfson and McAfee, as solutions, recommend massive increases in educational spending and a distribution of income via a more progressive tax regime. Lanier proposes that companies benefiting from the use of individual’s “data” provide those individuals with an income stream for its use (there is no discussion of whether or not this will be enough to provide the unemployment with an income to survive though). Ford proposes the Austian Economist Frederick Hayek’s idea of a “minimum income” whereby capital owners will be taxed (presumably heavily) in order to distribute income to the unemployed. Of course this implies that the wealthy are willing to do this without a fight or that they do not support a Pinochet of Franco to prevent this very thing from happening. Not something to have great confidence in.In short, the book comes to the same conclusion as many other authors regarding the impact of technology on employment and provides a different “solution” to the problem albeit this solution has significant problems as do the solutions proposed by the other authors mentioned above. Not a book to inspire much confidence in the future in. Then again the facts seem to be such that a dystopian future lies in the future for much of humanity.

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Humans Need Not Apply: A Guide to Wealth and Work in the Age of Artificial Intelligence PDF

Humans Need Not Apply: A Guide to Wealth and Work in the Age of Artificial Intelligence PDF

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